Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life

Newborns are highly susceptible to infectious diseases, which may be due to impaired immune responses. This study aims to characterize the ontogeny of neonatal TLR-based innate immunity during the first month of life. Cellularity and Toll-like receptor (TLR) agonist-induced cytokine production were...

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Hlavní autoři: Belderbos, M.E., van Bleek, G.M., Levy, O., Blanken, M.O., Houben, M.L., Schuijff, L., Kimpen, J.L.L., Bont, L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892115/
https://ncbi.nlm.nih.gov/pubmed/19648060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.07.003
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