Low-Dose LPS Induces Tolerogenic Treg Skewing in Asthma

The mechanism(s) underlying endotoxin tolerance in asthma remain elusive. As the endotoxin lipopolysaccharide (LPS) affects the expression of the regulatory T-cell (Treg)-suppressive glucocorticoid-induced tumor necrosis factor receptor ligand (GITRL) on antigen-presenting dendritic cells (DCs), we...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ding, Fengxia, Liu, Bo, Niu, Chao, Wang, Ting, Wang, Yaping, Geng, Gang, Tian, Daiyin, Dai, Jihong, Fu, Zhou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7538595/
https://ncbi.nlm.nih.gov/pubmed/33072079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02150
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