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Sequence features that drive human promoter function and tissue specificity

Promoters are important regulatory elements that contain the necessary sequence features for cells to initiate transcription. To functionally characterize a large set of human promoters, we measured the transcriptional activities of 4575 putative promoters across eight cell lines using transient tra...

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Hlavní autoři: Landolin, Jane M., Johnson, David S., Trinklein, Nathan D., Aldred, Shelly F., Medina, Catherine, Shulha, Hennady, Weng, Zhiping, Myers, Richard M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892090/
https://ncbi.nlm.nih.gov/pubmed/20501695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.100370.109
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