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Androgen Excess Produces Systemic Oxidative Stress and Predisposes to β-Cell Failure in Female Mice
In women, excess production of the male hormone, testosterone (T), is accompanied by insulin resistance. However, hyperandrogenemia is also associated with β-cell dysfunction and type 2 diabetes raising the possibility that androgen receptor (AR) activation predisposes to β-cell failure. Here, we te...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892018/ https://ncbi.nlm.nih.gov/pubmed/20585581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011302 |
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