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Potentiation of neutrophil cyclooxygenase-2 by adenosine: an early anti-inflammatory signal

Neutrophils, which are often the first to migrate at inflamed sites, can generate leukotriene B(4) from the 5-lipoxygenase pathway and prostaglandin E(2) through the inducible cyclooxygenase-2 pathway. Adenosine, an endogenous autacoid with several anti-inflammatory properties, blocks the synthesis...

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Detalhes bibliográficos
Main Authors: Cadieux, Jean-Sébastien, Leclerc, Patrick, St-Onge, Mireille, Dussault, Andrée-Anne, Laflamme, Cynthia, Picard, Serge, Ledent, Catherine, Borgeat, Pierre, Pouliot, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891968/
https://ncbi.nlm.nih.gov/pubmed/15769843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.01737
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