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Nuclear IRS-1 predicts tamoxifen response in patients with early breast cancer
Insulin receptor substrate-1 (IRS-1) is a cytoplasmic scaffolding protein that is phosphorylated by insulin-like growth factor-I receptor and recruits downstream effectors. Recent evidence suggests that IRS-1 has a nuclear localization and function. Here we investigated whether nuclear and cytoplasm...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891842/ https://ncbi.nlm.nih.gov/pubmed/19924529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0632-6 |
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