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The Enteropathogenic E. coli Effector EspF Targets and Disrupts the Nucleolus by a Process Regulated by Mitochondrial Dysfunction

The nucleolus is a multifunctional structure within the nucleus of eukaryotic cells and is the primary site of ribosome biogenesis. Almost all viruses target and disrupt the nucleolus—a feature exclusive to this pathogen group. Here, using a combination of bio-imaging, genetic and biochemical analys...

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Autors principals: Dean, Paul, Scott, Jon A., Knox, Andrew A., Quitard, Sabine, Watkins, Nicholas J., Kenny, Brendan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891835/
https://ncbi.nlm.nih.gov/pubmed/20585567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000961
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