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Synaptic Correlates of Increased Cognitive Vulnerability with Aging: Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1

Variability in cognitive functioning increases markedly with age, as does cognitive vulnerability to physiological and psychological challenges. Exploring the basis of this vulnerability may provide important insights into the mechanisms underlying aging-associated cognitive decline. As we have prev...

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Hlavní autoři: Chapman, Timothy R., Barrientos, Ruth M., Ahrendsen, Jared T., Maier, Steven F., Patterson, Susan L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891807/
https://ncbi.nlm.nih.gov/pubmed/20519534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5172-09.2010
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