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Synaptic Correlates of Increased Cognitive Vulnerability with Aging: Peripheral Immune Challenge and Aging Interact to Disrupt Theta-Burst Late-Phase Long-Term Potentiation in Hippocampal Area CA1

Variability in cognitive functioning increases markedly with age, as does cognitive vulnerability to physiological and psychological challenges. Exploring the basis of this vulnerability may provide important insights into the mechanisms underlying aging-associated cognitive decline. As we have prev...

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Detalhes bibliográficos
Main Authors: Chapman, Timothy R., Barrientos, Ruth M., Ahrendsen, Jared T., Maier, Steven F., Patterson, Susan L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891807/
https://ncbi.nlm.nih.gov/pubmed/20519534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5172-09.2010
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