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Atheroprone Hemodynamics Regulate Fibronectin Deposition to Create Positive Feedback that Sustains Endothelial Inflammation
RATIONALE: The extracellular matrix protein, fibronectin (FN), is focally deposited in regions of atherosclerosis where it contributes to inflammatory signaling. OBJECTIVE: To elucidate the mechanism by which FN deposition is regulated by local shear stress patterns, its dependence on PECAM-1 mechan...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891748/ https://ncbi.nlm.nih.gov/pubmed/20378855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.216283 |
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