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Rosiglitazone reverses endothelial dysfunction but not remodeling of femoral artery in Zucker diabetic fatty rats

OBJECTIVES: Endothelial dysfunction precedes atherogenesis and clinical complications in type 2 diabetes. The vascular dysfunction in Zucker diabetic fatty (ZDF) rats was evaluated at different ages along with the effect of treatment with rosiglitazone (Rosi) on endothelial function and mechanical r...

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Bibliografiske detaljer
Main Authors: Lu, Xiao, Guo, Xiaomei, Karathanasis, Sotirios K, Zimmerman, Karen M, Onyia, Jude E, Peterson, Richard G, Kassab, Ghassan S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891691/
https://ncbi.nlm.nih.gov/pubmed/20482873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-9-19
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