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Acute Toxicity of 3,3′,4,4′,5-Pentachlorobiphenyl (PCB 126) in Male Sprague-Dawley Rats: Effects on Hepatic Oxidative Stress, Glutathione and Metals Status

Although polychlorinated biphenyl (PCBs) production, and new uses for PCBs, was halted in the 1970s in the United States, PCBs continue to be used in closed systems and persist in the environment, accumulating in fatty tissues. PCBs are efficacious inducers of drug metabolism and may increase oxidat...

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Detalhes bibliográficos
Main Authors: Lai, Ian, Chai, Yingtao, Simmons, Don, Luthe, Gregor, Coleman, Mitchell C., Spitz, Douglas, Haschek, Wanda M., Ludewig, Gabriele, Robertson, Larry W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891598/
https://ncbi.nlm.nih.gov/pubmed/19969354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2009.11.002
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