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Regulation of paraoxonase 1 (PON1) in PCB 126-exposed male Sprague Dawley rats
3,3′,4,4′,5-Pentachlorobiphenyl (PCB 126), an aryl hydrocarbon receptor (AhR) agonist and most potent dioxin-like PCB congener, significantly alters gene expression, lipid metabolism, and oxidative stress in the liver. PON1, an antioxidant and anti-atherogenic enzyme, is produced in the liver and se...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288253/ https://ncbi.nlm.nih.gov/pubmed/22266287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2012.01.003 |
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