MODULATION OF HSP27 ALTERS HYPOXIA-INDUCED ENDOTHELIAL PERMEABILITY AND RELATED SIGNALING PATHWAYS

This manuscript describes how the permeability of pulmonary artery microvascular endothelial cell (RPMEC) monolayer is elevated by hypoxia and the role played by HSP27 phosphorylation. p38 MAP kinase activation leading to HSP27 phosphorylation was previously shown by our laboratory to alter the acti...

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Autors principals: Liu, Tiegang, Guevara, Oscar E., Warburton, Rod R., Hill, Nicholas S., Gaestel, Matthias, Kayyali, Usamah S.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891512/
https://ncbi.nlm.nih.gov/pubmed/19373869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21773
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