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Smooth Muscle α-Actin Expression and Myofibroblast Differentiation by TGFβ are Dependent Upon MK2

Fibroblasts play a major role in processes such as wound repair, scarring, and fibrosis. Differentiation into myofibroblasts, characterized by upregulation of smooth muscle α-actin (smα) in response to profibrotic agents such as TGFβ is believed to be an important step in fibrosis. Therefore, elucid...

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Hlavní autoři: Sousa, Anne Marie, Liu, Tiegang, Guevara, Oscar, Stevens, JoAnne, Fanburg, Barry L., Gaestel, Matthias, Toksoz, Deniz, Kayyali, Usamah S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586991/
https://ncbi.nlm.nih.gov/pubmed/17163490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21154
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