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Age-Dependent Deamidation of Lifelong Proteins in the Human Lens

PURPOSE. Deamidation is a common posttranslational modification in human lens crystallins and may be a key factor in the age-related denaturation of such lifelong proteins. The aim of this study was to identify the sites of deamidation in older lenses. METHODS. High-performance liquid chromatography...

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Detaylı Bibliyografya
Asıl Yazarlar: Hains, Peter G., Truscott, Roger J. W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Association for Research in Vision and Ophthalmology, Inc. 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891470/
https://ncbi.nlm.nih.gov/pubmed/20053973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4308
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