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PEGylated Dendritic Unimolecular Micelles as Versatile Carriers for Ligands of G Protein-Coupled Receptors

Despite its widespread application in nanomedicine, poly(ethylene glycol) (PEG) is seldom used for covalent modification of ligands for G protein-coupled receptors (GPCRs) due to potential steric complications. In order to study the influence of PEG chains on the biological activity of GPCR ligands...

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Detalhes bibliográficos
Main Authors: Kim, Yoonkyung, Hechler, Béatrice, Gao, Zhan-Guo, Gachet, Christian, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891302/
https://ncbi.nlm.nih.gov/pubmed/19785401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc9001689
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