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A recombinant sialidase fusion protein effectively inhibits human parainfluenza viral infection in vitro and in vivo
BACKGROUND: The first step in infection by human parainfluenza viruses (HPIVs) is binding to the surface of respiratory epithelial cells via interaction between viral receptor-binding molecules and sialic acid-containing receptors. DAS181, a recombinant sialidase protein containing the catalytic dom...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891144/ https://ncbi.nlm.nih.gov/pubmed/20533871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/653621 |
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