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Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells

Prostate tumorigenesis is coupled with an early metabolic switch in transformed prostate epithelial cells that effectively increases their mitochondrial bioenergetic capacity. The synthetic retinoid N-(4-hydroxyphenyl)retinamide (4HPR) inhibits prostate cancer development in vivo, and triggers react...

詳細記述

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書誌詳細
主要な著者: Hail, Numsen, Chen, Ping, Kepa, Jadwiga J.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891029/
https://ncbi.nlm.nih.gov/pubmed/19421858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-009-0356-4
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