Estradiol-induced desensitization of 5-HT(1A) receptor signaling in the paraventricular nucleus of the hypothalamus is independent of estrogen receptor-beta

Estradiol regulates serotonin 1A(5-HT(1A)) receptor signaling. Since desensitization of 5-HT(1A) receptors may be an underlying mechanism by which selective serotonin reuptake inhibitors (SSRIs) mediate their therapeutic effects and combining estradiol with SSRIs enhances the efficacy of the SSRIs,...

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Main Authors: Rossi, Dania V., Dai, Ying, Thomas, Peter, Carrasco, Gonzalo A., DonCarlos, Lydia L., Muma, Nancy A., Li, Qian
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891004/
https://ncbi.nlm.nih.gov/pubmed/20138435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2010.01.003
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