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GPR30 is necessary for estradiol-induced desensitization of 5-HT(1A) receptor signaling in the paraventricular nucleus of the rat hypothalamus

Estrogen therapy used in combination with selective serotonin reuptake inhibitor (SSRI) treatment improves SSRI efficacy for the treatment of mood disorders. Desensitization of serotonin 1A (5-HT(1A)) receptors, which takes one to two weeks to develop in animals, is necessary for SSRI therapeutic ef...

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Autors principals: McAllister, C.E., Creech, R., Kimball, P., Muma, N., Li, Q.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3342396/
https://ncbi.nlm.nih.gov/pubmed/22265196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2011.12.018
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