Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax

Cholera toxin (CT) elicits a mucosal immune response in mice when used as a vaccine adjuvant. The mechanisms by which CT exerts its adjuvant effects are incompletely understood. We show that protection against inhalation anthrax by an irradiated spore vaccine depends on CT-mediated induction of IL-1...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Datta, Sandip K., Sabet, Mojgan, Nguyen, Kim Phung L., Valdez, Patricia A., Gonzalez-Navajas, Jose M., Islam, Shamima, Mihajlov, Ivan, Fierer, Joshua, Insel, Paul A., Webster, Nicholas J., Guiney, Donald G., Raz, Eyal
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890829/
https://ncbi.nlm.nih.gov/pubmed/20479237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002348107
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