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Inhibition of lung tumor growth by complex pulmonary delivery of drugs with oligonucleotides as suppressors of cellular resistance

Development of cancer cell resistance, low accumulation of therapeutic drug in the lungs, and severe adverse treatment side effects represent main obstacles to efficient chemotherapy of lung cancer. To overcome these difficulties, we propose inhalation local delivery of anticancer drugs in combinati...

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Hlavní autoři: Garbuzenko, Olga B., Saad, Maha, Pozharov, Vitaly P., Reuhl, Kenneth R., Mainelis, Gediminas, Minko, Tamara
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890783/
https://ncbi.nlm.nih.gov/pubmed/20498076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004604107
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