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Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems

Resistance nodulation cell division (RND)-based efflux complexes mediate multidrug and heavy-metal resistance in many Gram-negative bacteria. Efflux of toxic compounds is driven by membrane proton/substrate antiporters (RND protein) in the plasma membrane, linked by a membrane fusion protein (MFP) t...

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Detalhes bibliográficos
Main Authors: De Angelis, Fabien, Lee, John K., O'Connell, Joseph D., Miercke, Larry J. W., Verschueren, Koen H., Srinivasan, Vasundara, Bauvois, Cédric, Govaerts, Cédric, Robbins, Rebecca A., Ruysschaert, Jean-Marie, Stroud, Robert M., Vandenbussche, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890744/
https://ncbi.nlm.nih.gov/pubmed/20534468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1003908107
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