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Cα-trace model of the transmembrane domain of human copper transporter 1, motion and functional implications
The trimeric human copper transporter 1 (hCTR1) is essential for copper uptake and is implicated in sensitivity to chemotherapy drugs. Using the cryoelectron microscopy (cryoEM) map of hCTR1 and evolutionary data, we constructed a Cα-trace model of the membrane region. The model structure, supported...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890728/ https://ncbi.nlm.nih.gov/pubmed/20534491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914717107 |
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