Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro

BACKGROUND: Heat shock protein 27 (Hsp27), a member of the small heat shock protein family, is an apoptosis regulator. Our previous proteomic study showed that Hsp27 mainly expressed in human oocyte, and that Hsp27 expression was downregulated in the ovaries derived from women with the polycystic ov...

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Hlavní autoři: Liu, Jin-Juan, Ma, Xiang, Cai, Ling-Bo, Cui, Yu-Gui, Liu, Jia-Yin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890611/
https://ncbi.nlm.nih.gov/pubmed/20465849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-8-47
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