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Downregulation of both gene expression and activity of Hsp27 improved maturation of mouse oocyte in vitro

BACKGROUND: Heat shock protein 27 (Hsp27), a member of the small heat shock protein family, is an apoptosis regulator. Our previous proteomic study showed that Hsp27 mainly expressed in human oocyte, and that Hsp27 expression was downregulated in the ovaries derived from women with the polycystic ov...

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Detalhes bibliográficos
Main Authors: Liu, Jin-Juan, Ma, Xiang, Cai, Ling-Bo, Cui, Yu-Gui, Liu, Jia-Yin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890611/
https://ncbi.nlm.nih.gov/pubmed/20465849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-8-47
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