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Towards the Rational Design of a Candidate Vaccine against Pregnancy Associated Malaria: Conserved Sequences of the DBL6ε Domain of VAR2CSA

BACKGROUND: Placental malaria is a disease linked to the sequestration of Plasmodium falciparum infected red blood cells (IRBC) in the placenta, leading to reduced materno-fetal exchanges and to local inflammation. One of the virulence factors of P. falciparum involved in cytoadherence to chondroiti...

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Hlavní autoři: Badaut, Cyril, Bertin, Gwladys, Rustico, Tatiana, Fievet, Nadine, Massougbodji, Achille, Gaye, Alioune, Deloron, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890577/
https://ncbi.nlm.nih.gov/pubmed/20585655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011276
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