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The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells

OBJECTIVES: To explore the function of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells, and discuss the signal transduetion mechanism of HepG2 cells in the apoptosis process induced by DADS by using the inhibitors of p38MAPK (SB203580) and caspase-3 (Z-DEVD-FMK). METHODS: After...

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Autors principals: Ji, Chunxiao, Ren, Fenglian, Ma, Heng, Xu, Ming
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890544/
https://ncbi.nlm.nih.gov/pubmed/20478073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-50
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