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The roles of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells

OBJECTIVES: To explore the function of p38MAPK and caspase-3 in DADS-induced apoptosis in human HepG2 cells, and discuss the signal transduetion mechanism of HepG2 cells in the apoptosis process induced by DADS by using the inhibitors of p38MAPK (SB203580) and caspase-3 (Z-DEVD-FMK). METHODS: After...

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Autori principali: Ji, Chunxiao, Ren, Fenglian, Ma, Heng, Xu, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890544/
https://ncbi.nlm.nih.gov/pubmed/20478073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-29-50
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