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Induction of protective autophagy against apoptosis in HepG2 cells by isoniazid independent of the p38 signaling pathway
Isoniazid (INH), one of the first-line anti-tuberculosis drugs, is adversely associated with hepatotoxicity in the clinic. However, the detailed mechanism of this side effect is still unclear. The traditional theory that cytochrome P450 2E1 is involved in INH-induced hepatotoxicity remains controver...
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| Pubblicato in: | Toxicol Res (Camb) |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6062403/ https://ncbi.nlm.nih.gov/pubmed/30090405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5tx00470e |
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