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A muscle-specific knockout implicates nuclear receptor coactivator MED1 in the regulation of glucose and energy metabolism

As conventional transcriptional factors that are activated in diverse signaling pathways, nuclear receptors play important roles in many physiological processes that include energy homeostasis. The MED1 subunit of the Mediator coactivator complex plays a broad role in nuclear receptor-mediated trans...

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Hlavní autoři: Chen, Wei, Zhang, Xiaoting, Birsoy, Kivanc, Roeder, Robert G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890439/
https://ncbi.nlm.nih.gov/pubmed/20479251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005626107
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