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Signaling properties of a covalent modification cycle are altered by a downstream target
We used a model system of purified components to explore the effects of a downstream target on the signaling properties of a covalent modification cycle, an example of retroactivity. In the experimental system used, a bifunctional enzyme catalyzed the modification and demodification of its substrate...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2890436/ https://ncbi.nlm.nih.gov/pubmed/20479260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913815107 |
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