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Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways

The balance between anabolic and catabolic signaling pathways is critical in maintaining cartilage homeostasis and its disturbance contributes to joint diseases such as osteoarthritis (OA). A unique mechanism that modulates the activity of cell signaling pathways is controlled by extracellular hepar...

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Bibliografische gegevens
Hoofdauteurs: Otsuki, Shuhei, Hanson, Sarah R., Miyaki, Shigeru, Grogan, Shawn P., Kinoshita, Mitsuo, Asahara, Hiroshi, Wong, Chi-Huey, Lotz, Martin K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890424/
https://ncbi.nlm.nih.gov/pubmed/20479257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913897107
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