MicroRNA-140 plays dual roles in both cartilage development and homeostasis

Osteoarthritis (OA), the most prevalent aging-related joint disease, is characterized by insufficient extracellular matrix synthesis and articular cartilage degradation, mediated by several proteinases, including Adamts-5. miR-140 is one of a very limited number of noncoding microRNAs (miRNAs) speci...

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Detalhes bibliográficos
Main Authors: Miyaki, Shigeru, Sato, Tempei, Inoue, Atsushi, Otsuki, Shuhei, Ito, Yoshiaki, Yokoyama, Shigetoshi, Kato, Yoshio, Takemoto, Fuko, Nakasa, Tomoyuki, Yamashita, Satoshi, Takada, Shuji, Lotz, Martin K., Ueno-Kudo, Hiroe, Asahara, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878654/
https://ncbi.nlm.nih.gov/pubmed/20466812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1915510
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