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Interaction between retroviral U5 RNA and the T psi C loop of the tRNA(Trp) primer is required for efficient initiation of reverse transcription.

The 5' end of avian sarcoma and leukosis virus RNA near the primer binding site forms two RNA secondary structures, U5-inverted repeat (U5-IR) and U5-leader stems, which are required for efficient initiation of reverse transcription. Lying between these two secondary structures is a 7-base sequence...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Aiyar, A, Cobrinik, D, Ge, Z, Kung, H J, Leis, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1992
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC289042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1548772/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.2464-2472.1992
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