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Phylogeny and Function of the Invertebrate p53 Superfamily

The origin of the p53 superfamily predates animal evolution and first appears in unicellular Flagellates. Invertebrate p53 superfamily members appear to have a p63-like domain structure, which seems to be evolutionarily ancient. The radiation into p53, p63, and p73 proteins is a vertebrate invention...

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Detalhes bibliográficos
Main Authors: Rutkowski, Rachael, Hofmann, Kay, Gartner, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890203/
https://ncbi.nlm.nih.gov/pubmed/20595397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001131
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