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Homeodomain-interacting protein kinase 2 plays an important role in normal terminal erythroid differentiation

Gene-targeting experiments report that the homeodomain-interacting protein kinases 1 and 2, Hipk1 and Hipk2, are essential but redundant in hematopoietic development because Hipk1/Hipk2 double-deficient animals exhibit severe defects in hematopoiesis and vasculogenesis, whereas the single knockouts...

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Библиографические подробности
Главные авторы: Hattangadi, Shilpa M., Burke, Karly A., Lodish, Harvey F.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890178/
https://ncbi.nlm.nih.gov/pubmed/20231426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235093
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