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Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

As the principal component of the membrane skeleton, spectrin confers integrity and flexibility to red cell membranes. Although this network involves many interactions, the most common hemolytic anemia mutations that disrupt erythrocyte morphology affect the spectrin tetramerization domains. Althoug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ipsaro, Jonathan J., Harper, Sandra L., Messick, Troy E., Marmorstein, Ronen, Mondragón, Alfonso, Speicher, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890174/
https://ncbi.nlm.nih.gov/pubmed/20197550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261396
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