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Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

As the principal component of the membrane skeleton, spectrin confers integrity and flexibility to red cell membranes. Although this network involves many interactions, the most common hemolytic anemia mutations that disrupt erythrocyte morphology affect the spectrin tetramerization domains. Althoug...

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Autori principali: Ipsaro, Jonathan J., Harper, Sandra L., Messick, Troy E., Marmorstein, Ronen, Mondragón, Alfonso, Speicher, David W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890174/
https://ncbi.nlm.nih.gov/pubmed/20197550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261396
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