Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex

As the principal component of the membrane skeleton, spectrin confers integrity and flexibility to red cell membranes. Although this network involves many interactions, the most common hemolytic anemia mutations that disrupt erythrocyte morphology affect the spectrin tetramerization domains. Althoug...

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Detalhes bibliográficos
Main Authors: Ipsaro, Jonathan J., Harper, Sandra L., Messick, Troy E., Marmorstein, Ronen, Mondragón, Alfonso, Speicher, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890174/
https://ncbi.nlm.nih.gov/pubmed/20197550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261396
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