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Mesenchymal Stem Cells Expressing Osteogenic and Angiogenic Factors Synergistically Enhance Bone Formation in a Mouse Model of Segmental Bone Defect

The potential of mesenchymal stem cells (MSC) in tissue regeneration is increasingly gaining attention. There is now accumulating evidence that MSC make an important contribution to postnatal vasculogenesis. During bone development and fracture healing, vascularization is observed before bone format...

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Bibliographic Details
Main Authors: Kumar, Sanjay, Wan, Chao, Ramaswamy, Girish, Clemens, Thomas L, Ponnazhagan, Selvarangan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890123/
https://ncbi.nlm.nih.gov/pubmed/20068549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.315
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