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The Pivotal Roles of Mitochondria in Cancer: Warburg and Beyond and Encouraging Prospects for Effective Therapies

Tumors usurp established metabolic steps used by normal tissues for glucose utilization and ATP production that rely heavily on mitochondia and employ a route that, although involving mitochondria, includes a much greater dependency on glycolysis. First described by Otto Warburg almost nine decades...

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Detalhes bibliográficos
Main Authors: Mathupala, Saroj P., Ko, Young H., Pedersen, Peter L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890051/
https://ncbi.nlm.nih.gov/pubmed/20381449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2010.03.025
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