Differential vulnerability of neurons in Huntington's disease: The role of cell type-specific features

Abnormal expansion of a polyglutamine tract in huntingtin (Htt) protein results in Huntington's disease (HD), an autosomal dominant neurodegenerative disorder involving progressive loss of motor and cognitive function. Contrasting with the ubiquitous tissue expression of polyglutamine-expanded...

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Hlavní autoři: Han, Ina, You, YiMei, Kordower, Jeffrey H., Brady, Scott T., Morfini, Gerardo A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2890032/
https://ncbi.nlm.nih.gov/pubmed/20236390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06672.x
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