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Localization of BDNF mRNA with the Huntington's disease protein in rat brain

BACKGROUND: Studies have implicated reduced levels of brain-derived neurotrophic factor (BDNF) in the pathogenesis of Huntington's disease. Mutant huntingtin (Htt) protein was previously reported to decrease BDNF gene transcription and axonal transport of BDNF. We recently showed that wild-type...

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Detalhes bibliográficos
Main Authors: Ma, Bin, Culver, Brady P, Baj, Gabriele, Tongiorgi, Enrico, Chao, Moses V, Tanese, Naoko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889995/
https://ncbi.nlm.nih.gov/pubmed/20507609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-5-22
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