Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat liver

BACKGROUND: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However, experimental data usually contain potential sources of uncertainty and thus many experiments are now designed with repe...

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Bibliografiske detaljer
Main Authors: Nguyen, Tung T, Almon, Richard R, DuBois, Debra C, Jusko, William J, Androulakis, Ioannis P
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Methodology article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889936/
https://ncbi.nlm.nih.gov/pubmed/20500897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-279
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