Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat liver

BACKGROUND: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However, experimental data usually contain potential sources of uncertainty and thus many experiments are now designed with repe...

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Autors principals: Nguyen, Tung T, Almon, Richard R, DuBois, Debra C, Jusko, William J, Androulakis, Ioannis P
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Methodology article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889936/
https://ncbi.nlm.nih.gov/pubmed/20500897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-279
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