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Lipid receptors and islet function: therapeutic implications?
G-protein coupled receptors (GPCRs) are targets of approximately 30 % of currently marketed drugs. Over the last few years, a number of GPCRs expressed in pancreatic β cells and activated by lipids have been discovered. GPR40 was shown to be activated by medium- to long-chain fatty acids (FAs). It h...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2889915/ https://ncbi.nlm.nih.gov/pubmed/19817784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1463-1326.2009.01114.x |
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