A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma

BACKGROUND: The potential anti-cancer effects of mammalian target of rapamycin (mTOR) inhibitors are being intensively studied. To date, however, few randomised clinical trials (RCT) have been performed to demonstrate anti-neoplastic effects in the pure oncology setting, and at present, no oncology...

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Bibliografski detalji
Glavni autori: Schnitzbauer, Andreas A, Zuelke, Carl, Graeb, Christian, Rochon, Justine, Bilbao, Itxarone, Burra, Patrizia, de Jong, Koert P, Duvoux, Christophe, Kneteman, Norman M, Adam, Rene, Bechstein, Wolf O, Becker, Thomas, Beckebaum, Susanne, Chazouillères, Olivier, Cillo, Umberto, Colledan, Michele, Fändrich, Fred, Gugenheim, Jean, Hauss, Johann P, Heise, Michael, Hidalgo, Ernest, Jamieson, Neville, Königsrainer, Alfred, Lamby, Philipp E, Lerut, Jan P, Mäkisalo, Heikki, Margreiter, Raimund, Mazzaferro, Vincenzo, Mutzbauer, Ingrid, Otto, Gerd, Pageaux, Georges-Philippe, Pinna, Antonio D, Pirenne, Jacques, Rizell, Magnus, Rossi, Giorgio, Rostaing, Lionel, Roy, Andre, Turrion, Victor Sanchez, Schmidt, Jan, Troisi, Roberto I, van Hoek, Bart, Valente, Umberto, Wolf, Philippe, Wolters, Heiner, Mirza, Darius F, Scholz, Tim, Steininger, Rudolf, Soderdahl , Gunnar, Strasser, Simone I, Jauch, Karl-Walter, Neuhaus, Peter, Schlitt, Hans J, Geissler, Edward K
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2010
Teme:
Study Protocol
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889889/
https://ncbi.nlm.nih.gov/pubmed/20459775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-190
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