A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma

BACKGROUND: The potential anti-cancer effects of mammalian target of rapamycin (mTOR) inhibitors are being intensively studied. To date, however, few randomised clinical trials (RCT) have been performed to demonstrate anti-neoplastic effects in the pure oncology setting, and at present, no oncology...

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Detalhes bibliográficos
Main Authors: Schnitzbauer, Andreas A, Zuelke, Carl, Graeb, Christian, Rochon, Justine, Bilbao, Itxarone, Burra, Patrizia, de Jong, Koert P, Duvoux, Christophe, Kneteman, Norman M, Adam, Rene, Bechstein, Wolf O, Becker, Thomas, Beckebaum, Susanne, Chazouillères, Olivier, Cillo, Umberto, Colledan, Michele, Fändrich, Fred, Gugenheim, Jean, Hauss, Johann P, Heise, Michael, Hidalgo, Ernest, Jamieson, Neville, Königsrainer, Alfred, Lamby, Philipp E, Lerut, Jan P, Mäkisalo, Heikki, Margreiter, Raimund, Mazzaferro, Vincenzo, Mutzbauer, Ingrid, Otto, Gerd, Pageaux, Georges-Philippe, Pinna, Antonio D, Pirenne, Jacques, Rizell, Magnus, Rossi, Giorgio, Rostaing, Lionel, Roy, Andre, Turrion, Victor Sanchez, Schmidt, Jan, Troisi, Roberto I, van Hoek, Bart, Valente, Umberto, Wolf, Philippe, Wolters, Heiner, Mirza, Darius F, Scholz, Tim, Steininger, Rudolf, Soderdahl , Gunnar, Strasser, Simone I, Jauch, Karl-Walter, Neuhaus, Peter, Schlitt, Hans J, Geissler, Edward K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2889889/
https://ncbi.nlm.nih.gov/pubmed/20459775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-190
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