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Inhibition of poliovirus RNA synthesis by brefeldin A.

Brefeldin A (BFA), a fungal metabolite that blocks transport of newly synthesized proteins from the endoplasmic reticulum, was found to inhibit poliovirus replication 10(5)- to 10(6)-fold. BFA does not inhibit entry of poliovirus into the cell or translation of viral RNA. Poliovirus RNA synthesis, h...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Maynell, L A, Kirkegaard, K, Klymkowsky, M W
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288987/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1312615/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.4.1985-1994.1992
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