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Inhibition of poliovirus RNA synthesis by brefeldin A.

Brefeldin A (BFA), a fungal metabolite that blocks transport of newly synthesized proteins from the endoplasmic reticulum, was found to inhibit poliovirus replication 10(5)- to 10(6)-fold. BFA does not inhibit entry of poliovirus into the cell or translation of viral RNA. Poliovirus RNA synthesis, h...

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Bibliografiske detaljer
Main Authors: Maynell, L A, Kirkegaard, K, Klymkowsky, M W
Format: Artigo
Sprog:Inglês
Udgivet: 1992
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC288987/
https://ncbi.nlm.nih.gov/pubmed/1312615
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